StrataQuest APP analysis examples
In the following some examples for analyses done with StrataQuest APPs are shown.
IF Immune Status in situ APP: Distance of tumor cells from blood vessels
IF Immune Status in situ APP: Distance of tumor cells from blood vessels
The following example was analysed using a combination of the IF Immune Status in siu APP and the FL version of the Angio APP. It was done for the Johns Hopkins Hospital in New York.
The aim was to evaluate the distance of tumor cells from blood vessels within the tumor cell clusters.
Analysis of cyclic stain and bleach samples
Analysis of cyclic stain and bleach samples
Multi-epitope ligand cartography (MELC) is a technology using samples subjected to cycles of fluorescent staining, imaging and photobleaching. Each cycle can use an antibody for a different protein. The result is a set of images of the distributions of many proteins for the same samples.
IHC Meta.Cells APP: Stroma and tumor detection on morphological stains
IHC Meta.Cells APP: Stroma and tumor detection on morphological stains
One of the main strenghts of StrataQuest is the capability to segment morphological structures based on a morphological stain alone (i.e. without a specific staining of the structure to be detected).
In this case, the task was made more difficult due to many very thin areas of stroma.
IHC Immune Status in situ APP: Anti-CD3 positive cells in epithelial and interstitial tissues
IHC Immune Status in situ APP: Anti-CD3 positive cells in epithelial and interstitial tissues
The aim of the project was to quantify the distribution of anti-CD3 positive cells in and around the epithelial areas of prostate biopsies from a clinical study.
The biopsies were provided by the Medical University of Vienna.
