Intracellular Parasite APP

Leishmaniasis detection & analysis in cell culture and tissue

Leishmaniasis is a disease caused by protozoan parasites. Infected macrophages in cell culture:
leishmaniasis app
Cell detection with specific live / dead parasite stage combinations
leishmaniasis app
Mouse skin-draining lymph node stained with DAPI
resulting epithelial area detection
   

The APP was designed to assist in research into Leishmaniasis and can be adapted for research on other intracellular parasites.

Its main function is to automatically detect parasite stages in cell compartments and quantify them in context with specific immune markers. The parasite load and the status of parasite stages, eg. “alive / dead” can also be evaluated and all results can be output.

 

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