Tissue + Diagnostics = TissueGnostics

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TissueGnostics was established in 2003 after nearly a decade of basic research. The goal was to supply scientists with qualitative and observer independent results for cell and tissue analysis in tissue context and this in automated format and significantly less time.

Katja Österreicher, Georg Steiner and Dr. Rupert Ecker, the three co-founders of the company, with the aid of a dozen of development partners (Medical University Vienna, Memorial Sloan-Kettering Cancer Center New York, Ludwig Boltzmann Institute for Cancer Research, Vienna; Fred Hutchinson Cancer Center, Seattle; Brighamand Women`s Hospital, Boston; etc.) succeeded in reaching this target by 2005.

Since then TissueGnostics expanded worldwide, with subsidiaries in Romania, the US and more than 15 different distributors (incl. Japan, China, Taiwan, France, Russia, Korea, Australia, Philippines, Great Britain, Italy, Kuwait, etc.). In 2008/2009 TissueGnostics completed its product portfolio with the HemoFAXS, differentiated blood smear analysis system, setting a new standard in blood analysis.

The combination of modern and state-of-the art analysis methods for scientific and clinical use in tissue and cell based research with innovative and easy-to-handle software to ensure efficient and reliable diagnostics always was and will be the motivation behind TissueGnostics product developments.

Defining the Challenge

Light microscopy was introduced in 1595, pathological anatomy in 1761. Given the vast potential of modern technology, these methods of pathological diagnosis appear hopelessly outdated. Still, they continue to be used even for life-threatening diseases.

Science and technology have reached a level allowing detailed information to be collected from space telescopes or from robots on Mars. While these are wonderful achievements, other types of information have a substantially greater impact on our lives. It does seem strange, therefore, that the appearance and distribution of cells in diseased tissue should still be analyzed in roundabout verbal terms.

In clinical practice, no detailed information is supplied about the precise character of denatured cell patterns. Efforts are being made to change this situation, as demonstrated by significantly rising numbers of surgical specimens and biopsies referred for immunohistological analysis worldwide.

Despite a rapidly growing need to analyze cells in tissue (the volume to be handled is doubling every three years), analysis continues to be based on microscopic studies that are purely visual in nature. As a result, the information thus collected is relatively imprecise.

Facing the Challenge

Scientists Georg Steiner and Rupert Ecker have established TissueGnostics to face this challenge. Together with their team, they set out to develop adequate tools for the 21st century and to bring about change by offering these tools to physicians and researchers.

The task of diagnosing malignant tumors, autoimmune diseases and inflammatory processes has traditionally been accomplished by visual and verbal approximations. TissueGnostics has developed the first tools ever to supply exact data for rigorous scientific study.